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  • Writer's pictureClint Shakman

Is MK-677 (Ibutamoren) a SARM? Or HGH version of SARM?

Updated: Jul 23, 2023


I. Introduction


Have you ever heard of SARMs and HGH? If you’re into fitness or bodybuilding, these terms might ring a bell. SARMs, or Selective Androgen Receptor Modulators, are a type of drug that’s designed to have effects similar to those of anabolic steroids.


They’re often used by athletes and bodybuilders to increase muscle mass and improve performance.


On the other hand, HGH, or Human Growth Hormone, is a hormone naturally produced by the pituitary gland that plays a crucial role in growth, body composition, cell repair, and metabolism.


Now, let’s talk about MK-677, also known as Ibutamoren. It’s a substance that’s been making waves in the fitness and bodybuilding world.


Some people call it a SARM, while others insist it’s not. If you search Google for it, you’ll find conflicting opinions & articles on whether it’s a SARM or not!


So, what’s the deal? Is MK-677 a SARM or not? And what does it have to do with HGH? Let’s dive in and find out.


II. Is MK-677 a SARM?


A. Understanding MK-677


MK-677, also known as Ibutamoren, is a potent, long-acting, orally-active, selective, and non-peptide agonist of the ghrelin receptor. In simpler terms, it’s a substance that stimulates the release of growth hormone in the body. It’s often used by athletes and bodybuilders for its potential to increase lean body mass and improve recovery from workouts. But is it a SARM? The answer is a bit complicated.


B. How MK-677 works


MK-677 works by mimicking the action of the hormone ghrelin and binding to one of the ghrelin receptors (GHSR) in the brain. This action stimulates the release of growth hormone from the pituitary gland. Unlike traditional HGH injections or supplements, MK-677 stimulates the pituitary gland to produce more natural HGH. This is a key difference that sets MK-677 apart from other SARMs and HGH supplements.


C. The debate: Is MK-677 a SARM or not?


The debate over whether MK-677 is a SARM or not stems from its unique mechanism of action.


While it’s often grouped with SARMs due to its muscle-building effects, it doesn’t work in the same way as traditional SARMs.


Most SARMs work by selectively binding to androgen receptors in the body, which leads to increased muscle growth. MK-677, on the other hand, doesn’t bind to androgen receptors. Instead, it stimulates the release of growth hormone by mimicking the action of ghrelin.


So, is MK-677 a SARM? Technically, no. It’s actually classified as a growth hormone secretagogue, which means it stimulates the secretion of growth hormone. However, because of its muscle-building effects, it’s often grouped with SARMs in discussions about performance-enhancing substances.


In conclusion, while MK-677 shares some similarities with SARMs, it’s not a SARM in the traditional sense. It’s a unique substance with its own set of benefits and potential risks, which we’ll explore in the next sections of this article.


III. The Role of HGH in Bodybuilding & Performance Enhancement


A. Understanding HGH


Human Growth Hormone, often abbreviated as HGH, is a hormone that is naturally produced by our body’s pituitary gland. This hormone plays a pivotal role in our growth, the regeneration of cells, and the maintenance of healthy human tissue, which includes vital organs and the brain.


Additionally, HGH is known to boost muscle growth, enhance strength, improve performance during exercise, and aid in the recovery process from disease and injury. Here’s a study that delves into the role of HGH in the body.


B. The Synergy Between HGH and SARMs


Selective Androgen Receptor Modulators, or SARMs as they are commonly known, are a class of therapeutic compounds that have similar properties to anabolic agents, but with reduced androgenic properties.


They are designed to target the androgen receptors in bone and muscle cells, which results in enhanced muscle and bone growth.


Although SARMs and HGH operate through different mechanisms, they are frequently used in conjunction in the bodybuilding and fitness communities due to their synergistic effects on muscle growth and performance enhancement. (That’s why RAD 140, a SARM is often stacked with MK-677, a growth hormone secretagogue.)


HGH can amplify the effects of SARMs by promoting the growth of muscle and bone cells, enhancing recovery post-workouts, and boosting overall performance.


Conversely, SARMs can augment the effects of HGH by stimulating the androgen receptors in muscle and bone cells, leading to an even more significant increase in muscle and bone growth. This research provides more insight into the interaction between HGH and SARMs.


C. How MK-677 Influences HGH Production


MK-677, also known as Ibutamoren, is unique because it functions as a growth hormone secretagogue. This means it stimulates the secretion of growth hormone in the body.


It does this by mimicking the action of the hormone ghrelin and binding to the ghrelin receptor in the brain. This action stimulates the release of a series of hormones in the brain that ultimately result in an increase in HGH production by the pituitary gland.


Unlike other SARMs, MK-677 doesn’t directly affect the androgen receptors. Instead, it increases HGH levels, which then leads to the benefits associated with increased HGH, such as increased muscle growth, improved recovery, and enhanced performance.


IV. Benefits and Side Effects of MK-677


A. Potential Benefits of MK-677


MK-677 has several potential benefits, primarily related to its ability to increase HGH levels. These benefits include increased muscle growth, improved recovery from workouts, enhanced fat loss, better sleep quality, and improved skin and hair health.


Increased muscle growth is one of the most sought-after benefits of MK-677. By increasing HGH levels, MK-677 can stimulate the growth of new muscle cells, leading to increased muscle size and strength.


Improved recovery is another significant benefit. HGH is known to aid in recovery from workouts by promoting muscle and tissue repair. By increasing HGH levels, MK-677 can help users recover more quickly from their workouts, allowing them to train more frequently and intensively.


B. Possible Side Effects and Risks


While MK-677 has several potential benefits, it’s also important to be aware of the possible side effects and risks. Some users have reported side effects such as increased appetite, mild lower extremity edema, and muscle and joint pain.


In addition, because MK-677 increases HGH levels, it may also increase the risk of conditions associated with high HGH levels, such as diabetes and cancer. However, more research is needed to fully understand the long-term risks of MK-677 use.


It’s also important to note that MK-677 is currently not approved by the FDA, and its use is banned in many sports due to its performance-enhancing effects.


V. MK-677 vs. Traditional HGH Supplements


A. Comparing MK-677 and Traditional HGH Supplements


When it comes to boosting growth hormone levels, both MK-677 and traditional HGH supplements are popular choices. However, they work in different ways and have distinct advantages and disadvantages.


Traditional HGH supplements, often in the form of injections, directly introduce synthetic human growth hormone into the body. They are typically used in medicine to treat conditions that cause growth hormone deficiency.


However, they’ve also found a place in the fitness and bodybuilding world for their muscle-building and fat-burning properties.


On the other hand, MK-677, or Ibutamoren, doesn’t introduce any synthetic hormones into the body. Instead, it stimulates the body’s natural production of growth hormone by mimicking the action of the hormone ghrelin. This makes it a growth hormone secretagogue, a substance that causes another substance to be secreted.


B. The Advantages of MK-677 over HGH Injections


There are several reasons why many people prefer MK-677 over traditional HGH supplements.

1. Oral Administration: Unlike HGH injections, which need to be injected into the body, MK-677 is orally active. This means it can be taken by mouth, making it much more convenient and less invasive.


2. No Synthetic Hormones: MK-677 works by stimulating the body’s natural production of growth hormone, rather than introducing synthetic hormones into the body. This can lead to a more balanced and natural hormonal environment within the body


3. Longer Half-Life: MK-677 has a longer half-life than HGH, meaning it stays active in the body for a longer period. This allows for once-daily dosing, whereas HGH injections may require multiple doses, often 2 throughout the day.


4. Lower Cost: MK-677 is generally less expensive than HGH injections, making it a more cost-effective option for boosting growth hormone levels.


5. Fewer Side Effects: Because MK-677 stimulates the body’s natural production of growth hormone, it is often associated with fewer side effects than HGH injections. However, it’s important to note that any substance that alters hormone levels can have potential side effects and risks, and MK-677 is no exception.


In conclusion, while both MK-677 and traditional HGH supplements can be effective for boosting growth hormone levels, MK-677 offers several advantages that make it a popular choice among athletes and bodybuilders.


Despite being NOT a SARM, MK-677 or Ibutamoren, classified as a growth hormone secretagogue, is often grouped with SARMs in discussions about performance-enhancing substances because of its muscle-building effects!


VI. FAQs


A. Is MK-677 a SARM or steroid?


MK-677, also known as Ibutamoren, is often grouped with SARMs due to its muscle-building effects. However, it’s not a SARM in the traditional sense. Unlike SARMs, which selectively bind to androgen receptors in the body, MK-677 works by mimicking the hormone ghrelin and stimulating the release of growth hormone. It’s also not a steroid, as it doesn’t have the same structure or side effects associated with anabolic steroids.


B. Why isn’t MK-677 a SARM?


MK-677 isn’t classified as a SARM because it doesn’t work by binding to androgen receptors like traditional SARMs. Instead, it stimulates the release of growth hormone by mimicking the action of the hormone ghrelin. This makes it a growth hormone “secretagogue”, a substance that causes another substance to be secreted.


C. Is MK-677 good or bad for you?


Like any substance that alters hormone levels in the body, MK-677 can have both positive and negative effects. On the positive side, it can increase muscle growth, improve recovery from workouts, enhance fat loss, and improve sleep quality. However, it can also have potential side effects, such as increased appetite, mild lower extremity edema, and muscle and joint pain. It’s also not currently approved by the FDA, and its long-term effects are still being studied.


D. What is the SARMs version of HGH?


There isn’t a SARMs version of HGH per se, as SARMs and HGH work in different ways. However, MK-677 is often grouped with SARMs due to its muscle-building effects and its ability to stimulate the release of growth hormone, making it similar to HGH in some ways.


E. Is MK-677 legit?


Yes, MK-677 is a legitimate substance that has been studied for its ability to increase growth hormone levels. However, it’s important to note that it’s not currently approved by the FDA, and its use is banned in many sports due to its performance-enhancing effects.


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